Preheat oven to 475 F. Line a large baking sheet with parchment paper or use a silpat.
In a large bowl,whisk together the flour, baking powder, baking soda, sugar, salt, garlic powder and cayenne. Fold in the cheddar cheese.
In a separate bowl stir together the buttermilk and melted butter until the butter forms clumps.
Pour the buttermilk mixture into the flour mixture and mix gently with a spatula just until a dough forms and there are no dry ingredients remaining.
Lightly spray a 1/4 cup measuring cup with non-stick spray. Scoop out 1/4 cup of dough at a time and place on the prepared baking sheet, 1" apart.
Bake 12-15 minutes or until biscuits are golden brown.
Remove from oven and brush with melted butter parsley mixture.